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Test Code FLUPV Lupus Anticoagulant Evaluation with Reflex

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
FHEXC Hexagonal Phase Confirm No No
FCLOT Thrombin Clotting Time No No

Testing Algorithm

If the PTT-LA is >40, then the Hexagonal Phase Confirmation (FHEXC) will be performed at an additional charge.

If the Hexagonal Phase Confirm is positive or weakly positive, a Thrombin Clotting Time (FCLOT) will be performed at an additional charge.

If the DRVVT Screen is >45 then the DRVVT Confirmation (FDVTC) will be performed at an additional charge.

If the DRVVT Confirmation is positive, then the DRVVT 1:1 Mix (FDVTX) will be performed at an additional charge.

Reporting Name

Lupus Anticoagulant Eval w/Reflexes

Specimen Type

Plasma Na Cit

Specimen Required

3 mL platelet-poor plasma, shipped frozen. Draw blood into a 3.2% sodium citrate (light blue-top) tube. Centrifuge for 15 minutes at 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/uL).

Freeze immediately. Ship on dry ice.

Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma Na Cit Frozen 90 days

Reject Due To

Hemolysis Mild reject; Gross reject
Lipemia NA
Icterus NA
Other NA

Reference Values

Lupus Anticoagulant                  Not Detected


    This interpretation is based on the following test results:


PTT-LA  Screen                      ≤ 40 seconds

DRVVT Screen                       ≤ 45 seconds


Day(s) and Time(s) Performed

Monday through Saturday

Performing Laboratory

Quest Diagnostics Nichols Institute

CPT Code Information

85613/ Russell viper venom time (includes venom); diluted

85730/ Thromboplastin time, partial (PTT); plasma

85598/ Platelet neutralization (Hexagonal Phase Confirm) – (if appropriate)

85597/ Platelet neutralization (dRVVT Confirm) – (if appropriate)

85613/dRVVT 1:1 Dilution (if appropriate)

85670/Thrombin Clotting Time (if appropriate)


LOINC Code Information

Test ID Test Order Name Order LOINC Value
FLUPV Lupus Anticoagulant Eval w/Reflexes 75515-7


Result ID Test Result Name Result LOINC Value
Z0734 Lupus Anticoagulant 75514-0
Z0544 PTT-LA Screen 34571-0
Z0735 DRVVT Screen 6303-2

Method Name

Clot Detection

Secondary ID