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Test Code C1QFX C1q Complement, Functional, Serum

Reporting Name

C1Q Complement, Functional, S

Useful For

Diagnosis of first component of complement (C1) deficiency

 

Investigation of a patient with an absent total complement (CH50) level

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum Red


Advisory Information


The total complement (CH50) assay (COM / Complement, Total, Serum) should be used as a screen for suspected complement deficiencies before ordering individual complement component assays. A deficiency of an individual component of the complement cascade will result in an undetectable CH50.



Specimen Required


Patient Preparation: Fasting preferred

Supplies: Aliquot Tube, 5 mL (T465)

Collection Container/Tube: Red top

Submission Container/Tube: Plastic, 5 mL tube

Specimen Volume: 1 mL

Collection Instructions:

1. Immediately after specimen collection, place the tube on wet ice.

2. Centrifuge and separate serum from clot.

3. Immediately freeze specimen.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Frozen 14 days

Reference Values

34-63 U/mL

Day(s) and Time(s) Performed

Monday through Saturday; Continuous with a 3 p.m. cutoff

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

86161

LOINC Code Information

Test ID Test Order Name Order LOINC Value
C1QFX C1Q Complement, Functional, S 87722-5

 

Result ID Test Result Name Result LOINC Value
C1QFX C1Q Complement, Functional, S 87722-5

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Method Name

Automated Liposome Lysis Assay

Secondary ID

83374